Bacterial and viral infections continue to cause disastrous collapses of the aquaculture industry. Import regulations, consumer demands and sustainable management strategies restrict the number of drugs available to treat pathogens. Vaccines are in many fish species still limited and even ineffective in crustaceans, which lack a specific immune system similar to that of vertebrates. Therefore, aquaculture producers must consider genetics, seed stock quality, husbandry procedures and healthy nutrition as key tools to control disease. This talk reports on recent progress in the development of functional feed additives capable of keeping the bad bugs under control in shrimp and fish farming using multiple mode of actions.
Functional feeds containing gut health promotors allow the delivery of an adequate concentration of natural antimicrobial/anti-parasitic activities into the digestive system of fish and shrimp with every meal . These feeds are an important component of any strategy to prevent opportunistic bacterial diseases such as Vibriosis. However, the success of this approach will depend on the efficacy of the selected gut health promotor against the pathogenic bacteria involved. Synergistic blends of natural compounds can be selected on their bacteriostatic and bactericidal properties against a specific range of pathogenic bacteria in vitro. Recent research shows that apart from direct bactericide or bacteriostatic effects, selected combinations of antimicrobial compounds are at the basis of more complex mechanisms to steer microbiota composition, ie Quorum Sensing (QS) disruption

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